It was played on this date in 1933 at Comiskey Park in Chicago.
There were several Cubs on that first all-star team: Lon Warneke (who pitched 4 innings of one-run ball against the likes of Babe Ruth, Lou Gehrig & Jimmie Foxx), Gabby Hartnett (who struck out in his only at-bat) & Woody English (who didn't get to play in the game).
Babe Ruth hit a two run homer in the bottom of the third, but it wasn't against Warneke. Cardinals pitcher Wild Bill Hallahan served up the dinger to the Babe.
The American League won 4-2.